Automatic Pre-Filled Syringe Plunger Rod Insertion and Labelling Machine

Automatic Pre-Filled Syringe Plunger Rod Insertion and Labelling Machine consisting of the main structure covered polycarbonate cabinet and SS 304

Automatic Pre-Filled Syringe Plunger Rod Insertion and Labelling Machine

Automatic Pre-Filled Syringe Plunger Rod Insertion and Labelling Machine

USA Pack Machines LLC introduces the Automatic Pre-Filled Syringe Plunger Rod Insertion and Labelling Machine, a stateof-the-art solution engineered to streamline the syringe packaging process with unmatched precision, speed, and safety. This advanced machine ensures that every step, from handling to labelling, operates in a fully automated and aseptic environment.

Built with a polycarbonate-covered cabinet and SS 304 frame, the machine delivers both durability and hygiene, meeting the stringent requirements of modern pharmaceutical manufacturing. The system integrates a laminar airflow unit that protects syringes from contamination during operation, ensuring product safety. A robust filling head with individual servo motors guarantees precise dosing for each syringe, while the vacuum system and pneumatic components work together to provide reliable stoppering and sealing.

The machine is equipped with a user-friendly PLC and HMI control system, allowing operators to monitor and manage operations with ease. The AC drive and electrical panel enhance stability and efficiency, ensuring consistent performance across production runs. Syringes are smoothly transferred from the in-feed hopper, which accommodates stainless steel trays, directly into the processing unit. This design eliminates unnecessary handling, reducing human intervention and safeguarding
sterility.

Once filled and securely stoppered, the syringes move seamlessly to the outfeed collection tray. At this stage, the system automatically inserts plunger rods with precision-controlled tightening, ensuring consistency and usability. Following the plunger rod assembly, the machine applies labels with accuracy and speed, creating a fully finished syringe ready for packaging.

By automating the entire plunger rod insertion and labelling process, manufacturers benefit from reduced labor costs, faster turnaround, and higher throughput. More importantly, the sterile, hands-free operation enhances patient safety while maintaining compliance with global GMP and regulatory standards.

With its robust construction, advanced automation, and high operational efficiency, the Automatic Pre-Filled Syringe Plunger Rod Insertion and Labelling Machine from USA Pack Machines LLC empowers pharmaceutical companies to scale production without compromising quality. It stands as a reliable, future-ready investment for injectable product packaging.

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# Model Output Speed
1 UPML-PL-PFS Up to 120 PFS per minute @ 1 ml (Output may vary based on nature of the filling substance and volume)
  • The machine is manufactured or developed accordance with GMP standards.
  • The structure is made of SS 304 or cladded with SS 304.
  • Rigid vibration free construction for trouble free performance.
  • Machine without-feed trays for collection of syringe tub.
  • All contact parts SS 316L and non-contact parts are SS 304.
  • Machine suitable for different syringe size with help of change part and depends on characteristic of liquid.
  • Servo with syringes synchronized system for filling Accuracy.
  • Filling volume set with touch screen HMI.
  • Pneumatically controlled Stoppering mechanism.
  • Very easy & accurate electronic based volume setting of different pre-fill syringes.
  • Zero Dripping filling stations.
  • Diving system with the design of timer belt and Stepper Motor/pneumatic Control which has no Vibration and very smooth kind of filling, filling material must be Fill Centrally in the Syringe.
  • Design of Nozzles and adjustment of flow rate is very useful for filling with minimum Air Bubble / foaming in the Syringes.
  • Low air machine stop sensor.
  • LAF stop machine stop sensor.
  • Door interlocking system.
  • A suitable expandable PLC with programming & 7” colour touch screen HMI.
  • The Pharma grade silicon tubes are used for filling & CIP/SIP.
  • There is a very less product change over time due to very less usage of mechanical parts.
  • All liquid contact parts easily removable for cleaning and sterilization purpose.
  • Machine with LAF which can maintain class 100 condition (OPTIONAL).
  • Co eccentric nozzles for quick filling of liquids.
  • For different heights of syringes, the whole assembly can be moved upwards & downwards.
  • Production counter is given with password protection for daily track report.
  • The faults can be detected on the PLC touch screen HMI and can be attended easily.
  • The output speed can be appeared on HMI screen.
  • Very less mechanical adjustment required due to the special design.
  • User friendly and very less maintenance required.
  • NITROGEN FLUSHING SYSTEM [OPTIONAL]: The filling unit has an inbuilt system for nitrogen flush. The unique dual filling nozzle flushes nitrogen before filling followed by filling operation.
  • Most reliable & proven mechanical components such as pneumatics & CE certified electrical/electronic such as AC motor, AC Drives, PLC & HMI Touch screen, safety interlock & Sensors, MCB’s, relay etc.
Sample Products Pre Fill Syringes and Dental Cartridges
Sample Product Size 0.2 ml to 10 ml
Types of Drugs Highly Viscous, Semi-Viscous, Gel, Suspension, Oily, Aqueous
Output Up to 120 PFS per minute @ 1 ml (Output may vary based on nature of the filling substance and volume)
Filling Station 1 No., 2 No., 5 No. & 10 Nos.
Filling Capacity 0.5 ml onwards
Dosing accuracy ± 1%
Power Supply Three Phase, 440 V, 50 Hz (Stabilized)
Working height 850 mm ± 50 mm
Air consumption 5 CFM
Air supply 6 to 8 Kg / cm²
Nitrogen supply 5 CFM pressure (Customer scope)