R&D Prefilled Syringe (PFS) Machine

UPML R&D Prefilled Syringe (PFS) Machine suitable for 1–10 ml syringes with quick-change parts, delivering 15–20 devices per minute at 1 ml. Designed for aqueous drugs, it’s ideal for small-batch, high-precision R&D filling.

R&D Prefilled Syringe (PFS) Machine

R&D Prefilled Syringe (PFS) Machine

USA Pack Machines LLC presents the ACCUFILL RPFS R&D, a cutting-edge solution tailored for research and development teams as well as exhibit batch production. This compact and fully integrated system is meticulously engineered to handle prefilled syringes, pre-crimped cartridges, and vials up to 10 ml, making it an essential tool for small-batch, high-precision pharmaceutical applications.

Designed with versatility in mind, the R&D Prefilled Syringe Machine ensures seamless operation with pre-washed and sterilized devices, thereby maintaining the highest standards of hygiene and product safety. With its streamlined, space saving design, the system delivers reliable performance while fitting efficiently into R&D labs and cleanroom environments.

At the core of its functionality lies a peristaltic pump-driven filling station, which guarantees precise dosing for aqueous drugs and other formulations. Following this step, the system incorporates a rubber stopper placement station, which can be easily interchanged to accommodate vial applications with minimal change parts. Additionally, a cap sealing station secures each unit, ensuring product integrity throughout the entire packaging process.

Each operation is powered by servo motor synchronization, ensuring high accuracy, repeatability, and smooth integration of filling, stoppering, and sealing tasks. With this advanced level of control, the machine consistently delivers 15 to 20 devices per minute at 1 ml fill volume, making it the perfect choice for R&D-scale production where precision is critical.

Furthermore, the machine’s compact combo design minimizes footprint without compromising performance, offering pharmaceutical companies a cost-effective and scalable solution for their developmental needs. By eliminating unnecessary complexity, it enables researchers to focus on innovation while maintaining compliance with strict industry standards.

With its robust construction, intuitive PLC and HMI interface, and easy changeover features, the USA Pack Machines LLC ACCUFILL RPFS R&D ensures smooth operations, reduced downtime, and optimal productivity. Whether for clinical trials, stability studies, or product demonstrations, this system empowers pharmaceutical teams to bring new therapies to market with speed, accuracy, and confidence.

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# Model Output Speed
1 UPML-ACCUFILL RPFS R&D 15-20 Devices/ Minute L Volume @1ML Fill

Automation-B:

  • 7” Color display
  • Panel Accessories
  • Sensor
  • AC drive
  • PLC and modular

Filling Unit:

  • Peristaltic pump-based filling unit. OR servo-based syringe (0.5 ml to 5 ml)
  • Syringe up down through ball screw assembly.
  • Ball screw rotating by servo motor.
  • Ball screw mounting plate (aluminum and SS).

Linear Vibrator and Rotary Vibrator with Bowl Unit:

  • Linear vibrator for rubber stopper.
  • Linear vibrator for aluminium cap.
  • Rubber stopper rotary vibrator with bowl.
  • Aluminum chute for rubber stopper and aluminum cap.
  • SS 304 up-down pillar assembly for rubber stopper and aluminum cap vibrator bowl.
  • Sensor for rubber stopper in chute.

Basic Machine with Change Parts:

  • One set star wheel and back guide (material use black or white Delrin).

Output Speed 15-20 Devices/ Minute L Volume @1ML Fill

  • Machine output 15-20 PFS per minute for 1 ml syringe

Body Structure:

  • Square pipe structure 40*40*2.0 mm thick (material use SS 304).
  • Body doors 1.2 mm thickness (material use SS304).
  • Machine top plate (material use MS 10 mm with SS 1.5 mm cladding).
  • Door handles (material used-nylon.)

Security Enclosure:

  • Cabinet structure (material SS304)
  • Cabinet doors (material used – Polycarbonate/ toughened glass).
  • Door handles & hinges (material use-SS 304 & nylon).
  • Aesthetic look at door magnet assembly (self-developed).

Indicative Operation Process: PFS/ PRE-Crimped Cartridge

  • Syringes are loaded in the swipe-in slanting conveyor manually from where syringes are transferred to the central star wheel where the filling process is initiated.
  • After the filling cycle completion, the syringe moves to the next station where the stoppering process is completed.
  • A filled & stoppered syringe is released on the exit conveyor from where syringes are collated in the collection tray.

Indicative Operation Process: PFS/ PRE-Crimped Cartridge

  • Vials are loaded onto the tray manually from where vials are transferred to the central star wheel where the filling process is initiated.
  • After the filling cycle completion, the vial moves to the next station where the stoppering process is completed.
  • The finished vial is released on the exit conveyor from where syringes are collated in the collection tray for the cap sealing process.
Applicator Shape & MOC Pre-washed & sterilized PFS/ Vials/ Pre-Crimped Glass Cartridges
Volume of Syringes 1ml-10ml* Change Parts Supported
Filling Material Water Based Liquid/ Suspension/ Aqueous
Output Speed 15-20 devices per min @1ml for aqueous drug
Direction Left to Right
No. of Filling Station 1 NOS
No. of Rubber Stoppering Station 1 NOS
Direction of Movement Left to Right
Power Requirement 16 AMP (Main input supply cable 1.5 sq. mm 3 core)
Power Supply Single Phase/ 230 V AC/ 50 Hz
Accuracy ± 2%
Working Height 850 mm ± 50 mm Adjustable
Net Weight 1100 kg Approx.
Dimension 2000 mm (L) x 1000 mm (W) x 1950 mm (H) Approx.

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